The Crucible Essay Example for Free

The Crucible Essay In The Crucible, by Arthur Miller, John Proctor shows his protagonist character by the respectable and honorable man he lives to be. In order to understand why John Proctor is the protagonist of the story, a definition of the word protagonist is indispensable. A protagonist is essentially the main character of a story, mostly known as the good character. The author spends most of his time on him, and usually the character changes or evolves during the course of the novel. The protagonist is frequently the hero of the novel and rivals with the minor ambitious character also known as the antagonist. With many complex characteristics, he is the center of the plot. Proctor has failed in his marriage, been accused of witchery, and concludes his life with forgiveness. Proctor exemplifies true heroism in his acts of clamorous times. As Proctor’s truths of adultery are revealed, he settles these rumors with claiming that it is truthful. John Proctor is most likely the true protagonist. In the Crucible, Abigail Williams is portrayed as the antagonist of the allegory. Proctor cheats on his wife, Elizabeth, with Abigail while Elizabeth is ill. The story proceeds with Abigail becoming jealous and desiring John for herself. John shows that he regrets his affair by stating to Abigail, I will cut my arms off before I ever reach for you again. The focus of this sequence of events is how John deals with this situation. The Crucible literally means a hard test. His test is to overcome his troubles in his marriage and society. Society at this time is accusing its people of witchery. John works through his marriage problems and stumbles upon false accusations. As Abigail creates chaos throughout the town, the idea of witches has spread too. Proctor is accused of being a witch. He was chosen to be accused by the author because he is the protagonist. The focus is mainly on his life and his family. He chooses the right thing as he goes through the trials. He admits to his adultery with Abigail to prove that she lies. Proctor realizes what he has to do to save his wife. He is a hero by admitting his wrong doings and confessing his sorrow for acting upon them. Proctor learns to forgive through these trials. John knows how to represent his beliefs and stand up for his rights through forgiveness. After he admits to his sin, he is told to write on the church door for what he did. He refuses to after already admitting his actions. Proctor did not want to put his family to shame even more. I cannot mount the gibbet like a saint. It is fraud. Im not the man (Act 4, pg.109) He knows that God knows and forgives but he shall not exploit it for others to judge and assume. Proctor concludes his life being content with the final decision he has made. He shows that he is a hero to his family and neighbors. John Proctor shows many characteristics of a protagonist. He is a hero to many as he risks his life because he knows he believes in God. The story focuses on his marriage and the aftermath of the direction of his wrong doings. Often the novel will focus mainly on the protagonist’s personal situation. Proctor is the main character as Abigail Williams serves as antagonists throughout the story. She fights to break down Proctor and make him love her. Proctor prevails by doing the morally correct action by confessing and sticking to his beliefs. John Proctor displays qualities of a heroic protagonist.

Motivation Of Employees In The Hotel Industry Tourism Essay

Motivation Of Employees In The Hotel Industry Tourism Essay The last few decades have been characterised by a radical change in management perceptions about the importance of the work force in achievement of strategic objectives of business organisations. Management experts agree that in situations where competitors have similar financial resources and organisational infrastructures, competitive edge can be achieved only through well trained and intensely motivated employee forces. The hotel industry has grown remarkably in the last two decades. With the industry expanding exponentially, capacity builds ups in business and tourism centres have created enormous competition in all its segments. Whilst hotel managers strive to provide good physical facilities to their clients, it is widely accepted that excellence in service quality is best achieved through the efforts of employees to meet customer needs. Motivating employees is thus seen to be a critical task of hotel managers. The dissertation project aims to examine the importance of motivating employees in the hotel industry for the achievement of competitive advantage and the best possible ways and means of doing so. The last few decades, especially the period that commenced from the 1970s, have been characterised by radical changes in management perceptions about the importance of the work force in achieving the strategic objectives of business organisations.  [1]   Whilst traditional management theory treated workers, along with capital, land and machinery, as just one of the four important inputs of business enterprises, current management thought and practice, influenced on one hand by the opinions of experts like Drucker, Porter, Maslow and McGregor, and on the other by dramatically altered business conditions, perceive employees to be critical to organisational success and growth.  [2]   Contemporary developments like globalisation, economic liberalisation, the deconstruction of trade and physical barriers, technological advances, the spread of the internet, instantaneous communication technology, cheaper travel costs and the emergence of China and India as economic power houses have made the world intensely competitive and diminished the superiority of Western business organisations.  [3]  Management experts agree that in economic scenarios where competitors have the same sort of financial resources and organisational infrastructures, competitive edge is mainly achieved through well trained and intensely motivated employee forces.  [4]   The hotel industry has grown remarkably in the last two decades. Globalisation along with greater discretionary incomes in the populations of advanced and developing countries, cheaper travel, open borders and the opening of numerous business and tourists destinations have led to substantial increases in business travel and domestic and international tourism and created enormous opportunities for hotels. Aims and Objectives With the hotel industry expanding exponentially, capacity builds ups in business and tourism centres have created enormous competition in all sectors of the hotel industry.  [5]  Being service oriented in nature, hotels work towards achievement of service quality and improvement of customer satisfaction for achievement of competitive advantage.  [6]   Whilst hotel ownerships strive to provide good physical facilities to their clients, it is widely accepted that excellence in service quality is best achieved through the efforts of employees to meet customer needs  [7]  Motivating employees is thus seen to be a critical task of hotel managements.  [8]   This proposal aims to investigate the contribution of employees in achievement of profitability and competitive advantage in the hotel industry, the importance of motivation in improving employee performance, and the role of managers in motivating employees to improve their performance and commitment. Its objectives are elaborated as follows: To examine the ways and means in which employees can add to the service quality, efficiency, profitability and competitive advantage of the hotel industry. To examine the impact of motivation on the performance of hotel employees. To examine and assess the various ways of motivating employees. To examine the roles of managers in motivating hotel employees. 2. Literature Review Human resource management theory has changed radically over the past few decades. Whilst traditional HR theory was influenced and shaped by scientific management principles embodied in the approaches of Henry Ford and Fredrick Taylor for improvement of worker productivity, the post Second World War period saw the emergence of behavioural experts and psychologists like Maslow, McGregor, Herzberg and Vroom, who discarded Fordist and Taylorist principles and emphasised that worker performance could be much better enhanced by meeting the various needs of workers, training and developing them and empowering them to do their work to the best of their ability.  [9]   Experts like Maslow and Herzberg stress that worker motivation is critical to worker performance and organisational managements need to motivate members of their work force in carefully thought out, well planned and deliberately implemented ways. Maslowà ¢Ãƒ ¢Ã¢â‚¬Å¡Ã‚ ¬Ãƒ ¢Ã¢â‚¬Å¾Ã‚ ¢s theory of needs, McGregorà ¢Ãƒ ¢Ã¢â‚¬Å¡Ã‚ ¬Ãƒ ¢Ã¢â‚¬Å¾Ã‚ ¢s exposition of theory X and theory Y, Herzbergà ¢Ãƒ ¢Ã¢â‚¬Å¡Ã‚ ¬Ãƒ ¢Ã¢â‚¬Å¾Ã‚ ¢s detailing of hygiene and motivating factors, and Vroomà ¢Ãƒ ¢Ã¢â‚¬Å¡Ã‚ ¬Ãƒ ¢Ã¢â‚¬Å¾Ã‚ ¢s work on motivating employees deal with the various needs of workers and how they can best be motivated by organisational managements.  [10]   Extant HR theory also places great stress on the need of managers to know methods of motivation and use them appropriately in the work place.  [11]  The evolution of human resources as a management discipline has been characterised by numerous academic and research work on the best possible methods of motivating employees.  [12]   Employees are seen as key inputs in the hotel industry and most well known hotel chains like The Marriot, The Mandarin Orient and The Ritz Carlton are known to have very carefully thought out and well implemented employee performance improvement programmes.  [13]  Motivation plays a key role in such programmes and is a key responsibility of hotel managers.  [14]   The Ritz Carlton, the only two time winner of the famous Malcolm Baldridge awards for quality, is known to have an excellent employee training, development and motivation programme.  [15]  Employees at the Ritz Carlton are motivated through a complex system of policies and procedures that deal with remuneration, training, involvement, responsibility allocation, employee respect and empowerment.  [16]   Employee motivation and the responsibilities of managers in motivating employees are key areas of focus in hotel management theory.  [17]   3. Research Methodology Research Hypotheses The aims and objectives of the project, along with the information obtained during the course of review of available literature, lead to the following research hypotheses: Hypothesis 1: Employees are critical for the achievement of service quality, profitability and competitive advantage in the hotel industry Hypothesis 2: Employee motivation leads to improvement in employee performance Hypothesis 3: Managers can motivate hotel employees in various ways. Research Methods The choice and adoption of appropriate research methods for projects are essentially decided by the nature of the project and the resources available with the researcher.  [18]  With there being two basic methods of social research, namely the quantitative and qualitative approaches, the choice of an appropriate method for this assignment will be shaped by the research hypotheses elaborated above.  [19]   The research hypotheses essentially deal with issues and questions that are how, why and what in nature, and are thus best tackled by use of interpretative qualitative methods, rather than through analysis of the results of number based quantitative surveys.  [20]   Information for the project will be obtained from primary and secondary sources.  [21]  Primary information sources are those that provide information directly from people and organisations who form the subject of research, whereas secondary information is obtained from sources created by people, (e.g. authors, researchers, or media publications), who are unconnected with the research subject.  [22]   It is proposed to use both primary and secondary sources for this research project.  [23]  Whilst substantial information from secondary sources on human resource management, motivational theory, service quality, managerial responsibility and the responsibilities and methods of managers for motivating employees is available in the public domain, primary information can be obtained through study of hotel websites and interviews of people associated with the research subject.  [24]  With the hospitality industry now a globally important industry, a number of academic publications and research studies are available on different aspects of hotel management.  [25]  The study of such sources will enable the researcher to obtain accurate and extensive information on the subject under study.  [26]   The methodology entails the collection of primary and secondary data from the sources elaborated earlier, the qualitative interpretation of obtained information, and its detailed analysis for the purpose of examining the validity of the hypothesis.  [27]   Ethics Care will be taken to ensure that all ethical requirements regarding the conduct of research projects are followed, especially with regard to protection of the rights and confidentiality of primary respondents. Adequate care will be taken to ensure that appropriate credit is given to all information sources.  [28]   Constraints and Limitations The study will be limited by the amount of primary and secondary information accessed by the researcher, as well as the amount of cooperation provided by the primary respondents from the hotel industry. It is envisaged that obtaining appointments with hotel managers may be a difficult task and could delay the gathering of information and data. The researcher plans to start taking appointments with managers in the hotel industry at the earliest in order to maintain the research schedule. 4. Timeline The research is expected to take six months to complete. The timeline of the project is provided below. Function Month 1 Month 2 Month 3 Month 4 Month 5 Month 6 Determining of Secondary Information Sources * Study of Secondary Information Sources * * * Determination of Primary Information Sources * * Study of Primary Information Sources * Fixing of Appointments with Primary Respondents * * Conducting of Interviews * Collation of Secondary Information * Compilation of Literature Review * * Compilation of Primary Information * Collation of Data * Data Analysis and Interpretation * Preparation of Rough Draft of Dissertation * Discussion with Tutor * Preparation of Final Dissertation * Word Count: 1610 without Tables

Why is not ASEAN regionalism as successful as the EU

Why is not ASEAN regionalism as successful as the EU   Since the end of WWII, integration and regionalism has been the main focus for the study of international relations.   Peace was the main reason for creating a regional body, but since the fall of communism in the Soviet Union, the main focus on regionalism was on the economic.   The success of the integration in Europe had given the foundations of most of the earlier studies, which they tend to take Europe as a blueprint for the success in regionalism. Many third world regional bodies such as the ASEAN also look at Europe seriously because of its success.   By taking a comparative look at both organizations by their reasons to create a supranational body, the structures of both organizations; and evaluate them in terms of their successes, we can better understand both organizations. The integration process of Southeast Asia is very different from that of the EU in many ways that it creates the sense of uniqueness apart from the other regionalism around the world. Although it hopes to enjoy the same success as in Europe, there are many arguments whether it can achieve as much as Europe, such as in its past, the authoritarian style of governments, its economy structure, and its inability to solve disputes. The questions here lay in the future of ASEAN on which way is it going to go, and what it has to do to engulf successes of Europe. Right now regionalism that is undergoing in Southeast Asia is in a changing direction, economic success is seen as the main goal. The adaptation towards the European model acts as the guideline for the transformations. Nevertheless the need to understand the comparative work is very important towards future transformation in order to function as effectively as the EU model and to maintain the uniqueness of the ASIAN integration. The reasons behind ASEAN’s failure are the lack of institutions to enforce the structural co-operations from the members.   Part of understanding the background of both regions, looking i nto the history of the identity processing is necessary. There are debates about integration concerning the communal identities and the ideological structure that supports this. The comparative question over the identities of both organizations is why is it that the forming of the identity of Europe was more successful than the Southeast Asian region. What is the arguments concerning the identities of both organizations. With the EU, the question is based upon what are the factors that made up the European identity, and what determines what European is and what is not. Since there are many debates concerning that many of the benefits that helped built up the identity of Europe came from Asia, such as its polity, and its religion. The question concerning the ASEAN identity is whether there is a Southeast Asian identity in the first place and is the way things are set today, the proper way that things should be functioning? The fact that integration is a science that makes use of the pre-existing relationships between states members, an analysis of these prior relationships that build up both identities is critical in understanding the effectiveness of both organizations Research Questions Why is not ASEAN regionalism as successful as the EU? What are the main different characteristics of both organizations? What are the main similar characteristics of both organizations? Research Methodologies This study is a comparative analysis that focuses on secondary sources in order to obtain information pertaining the background, reasons, structures, and values of the EU and ASEAN. Hypotheses ASEAN regionalism is considered as a failure when compare to the EU in the degree of their reasons of their establishment, the differences in their values and structures. Reasons The European Union Security is the main concern for the EU since its beginning.   The threats form security exist both externally and internally.   The key actors here for the external security reasons were the Soviet Union, and the US, the threats of the Soviet Union for Europe was so great that America had to step in to help Europe in its rebuilding process in order to prevent Communist influences while keeping capitalism alive.   This involves pouring massive amount of money into reviving West Germany to an economically giant of Europe.   The formation of the EU was also received full support from the US, because of the integration process will benefit America by creating a bigger market for it to invest in, and a bigger trade bloc to trade to.   The forming of the EU will also allows the US to establish military bases in strategic locations in order to exercise its military power against Soviet threats. The building of the EU will also relieve the US from some of its responsibilities in t he world stage, creating a middle actor in the balancing of power from the US and the USSR.   Therefore the US support was very essential for the building of EU.   Internally, Europe at the time a war weary continent was going through a massive challenge in building itself.   Europe had gone through series of devastating wars; the most demolishing one of all was WWII.   After the end of the Second World War, most of Europes infrastructures were left destroyed from the strategic bombing from both the Allies, and the Nazi.   Europe was left to the state of rebuilding its infrastructure as same as its economy.   Most importantly it cannot afford another devastated war, the backdrop of this was the signing of the Coal and Steel Treaties, which was the major signing that will lead to the period of peace and security.   The Coal and Steel Treaties takes a look at the cause of European warfare in terms of the resources needed to build a war industry.   The main industry was steel and coal was needed to process it into weapons.   The idea was if Europe could break down the two industries, which were the resources that could lead to war and control and regulated it by a supranational governing body, then there will be a monitoring on the use of the two resources preventing another arm race from any country.   This is an example of a strong foundation of a strong supranational institution that limits some of the sovereignty that nation states use to have.   As later we will discuss the preambles written in this document in order to determine weather it was successful or not.   Although this treaty was not the foundation document of creating the EU, it was very important in the aspect of internal security and keeping peace and stability in the economy. ASEAN For SEA, security was also the main factor in forming a regional body.   Same as Europe, the Communist threats were the main threats from the external force as well as an internal force, so SEA had got a lot of support from America.   The theory behind this was called the Domino Effect Theory produced by George Kenneth, the secretary of state of the US administration during that time.   SEA was battling another front in the Cold War, and it was a potentially vulnerable front as well.   The fall of Vietnam then Laos then Cambodia gave the Domino effect theory its name, because countries who battle against communism in this region falls one by one similar to the dominoes, and the influence of the communism spread through the neighboring country.   Massive money was injected into the region in order to create strong capitalistic economic structures.   Military Dictatorship was very common in most of the countries, because it processed the strong authoritarian rule needed to counter communism.   External conflict lays solely on the threat from Vietnam, while an internal conflict was on the communist influences domestically that were big threats creating fragmentation in each country.   The evidence was the numbers of communist parties and their violence handling in each countries of SEA. For example, the bloodshed in Indonesia with General Suharto actions against PKI rallies which left many scholar to believe the number of death are between 200,000 to 500,000.    Although during this time, both regions are very similar in the external and internal reasons to strengthen co-operations in creating a secured community from communism, one major difference was that of the non-interference agreement signed by ASEAN members in the Bangkok Declaration, the founding treaties establishing ASEAN.   In Europe, the governments of the members had agreed in giving up limited sovereignty by creating supranational institutions to monitor, and to exercise its power such as the pooling of resources like coal and steel.   While ASEAN nations did not agreed on giving up any sovereignty by signing the non-interference agreement.   This will produce massive effects in the lacking of co-operations and monitoring body in ASEAN.   During this time each countries were focusing on building its own domestic economy by trading outside of their regions such as markets of Japan and the US rather than focusing on the intra trading activities.   Ironically ASEAN co-o perations was nothing more than an agreement not to co operate, focusing on building prosperity separately without intervening on each others affairs.   Until recently that ASEAN sees an essential need to integrate and co-operate regionally in order to prosper economically. Values In this part of the paper, we are looking at the completely different sets of values that will in turn influence the last point of the paper, which is organization structure drastically.   The contrast between two sets of values that lies in the organizations here is clear.   Regionalization of the SEA is very much different than the one of Europe. Because of the Asian way of thinking which tend to be authoritarian, many had argued that, SEA needed to find its own path rather than following Europes model of integration.   Unlike the EU, which had a strong foundation of regional/continental identity, the ASEAN identity had been a recent created identity.   The Southeast Asian people did not come up even with the technology employed to define national boarder lines but it was done from colonialism.   There was no common language like Europe had of Latin that was used to communicate in religion and states affairs.   There was no common religion like Christianity.   There w as no common law and order like Europe had from the Roman Empire or the establishment of democratic values from Greece.   Asian values tend to be authoritarian rather than liberalism in Europe. Authority is the most important thing above everything in Southeast Asia, while individualism and human rights is emphasized in Europe1.   The evidence determining this is in democracy, during the signing of the Treaty of Rome, each leader of the members were democratically elected leaders, while in Southeast Asia, leaders were military juntas and authoritarian ruler.   The reason behind this was the need for the strong ruling against the backdrop of communist threats from Indo China.   The military juntas were Field Marshall Thanom of Thailand, Marcos in the Phillippines, and Surhato in Indonesia, while the authoritarian leaders were Mahadthere in Malaysia, and Lee Guan Yuu of Singapore.   This is the very big difference we can see between the two different styles of polity.   Th is authoritarian value came from the pre-colonial period when the polities of SEA were in forms of Kingdoms and Sultanate states.   Power was circulated within the family like in the form of absolute monarchy.   Territories existed in a form of sphere of influence rather than a clear borderline.   This could explain the struggle of ASEAN nations to adapt to democracy during the post-colonial period.   Although democracy tendencies and structures were introduced and left behind by the colonial countries, the effect of communism just forced democracy backward, because of the need for a strong authoritarian rule to keep out communism This has made it more complicated during the post-Cold War era to switch from a military authoritarian rule to democracy.   This difference can be seen as authoritarianism of ASEAN versus democracy of EU, which contributed to the vast difference in value structures of both organizations.   In effect, the governments of ASEAN tend to focus domes tically in keeping their legitimacy and to remain in power rather than co-operating together.   As a result, this has made any regional interactions and decision-making done at the top level of the society by government leaders rather than benefitting people in all levels of the society.   This has made it acceptable for non- democratic countries like Burma, Cambodia, Vietnam, and Laos to later join.   With the EU, it is a completely different story, according to the Copenhagen Criteria, the EU does not allows the joining of a non democratic countries, the criteria also includes the respect of human rights in each member countries and the opening up of a free market. Having standards of criteria for acceptance makes cooperation easier for the EU, when compared to the ASEAN where similar common grounds and agreements cannot be found.   Prior to the European colonization, the polities of SEA were in a form of kingdom, which was ruled in the form of monarchies. There were no clear boundaries or drawn territory of these kingdoms. Rather, the influences of these kingdom existed in form of a sphere of influences, which were submitted to China. There were no common languages, religion or shared sense of identity like existed in Europe. Since the beginning, the creation of national identities had been defined and brought on by western civilization during colonialism. The territorial boundaries were purely derived from an imaginary concept by the process of the competition among Western colonizers to gain the economical edge. Therefore, the cooperation that we can see in this period of this region was not between one another, but rather towards external influence. And the conflict between the colonizers had fueled the sentiment towards fragmentation between each nation state. A good example would be the position of Tha iland who sits as a buffer state between the French in Indo-China and the British in Burma and Malaya. The movement that could indicate a certain level of interaction during the colonial period between member countries would be the struggle for independent movement against the colonizers. These interactions however were done in a very small level and tended to be in the underground. Colonization had brought Asia its creation of modern national identities, along with a strong sense of non-interference between states in this region. This is a clear example of how external forces played a significant influence upon the region.   As a result, an external conflict that Southeast Asian found itself upon would lead to an internal conflict in the region that will be potentially threatening during the post-war era. The rivalries between Thailand and Myanmar which had already been going on for the last fifty years along with current issues over the refugee and drug trafficking, the territor ial dispute between Malaysia and Indonesia over Sabah, and the genocidal conflict of Cambodia and Vietnam. These conflicts would prove to be issues that are obstacles for the regional body to climb. Nevertheless, the regional body had to be formed due to a-threatening-growing-Chinese-influences with the enthusiastic support by the U.S. in a plan to combated communism. Although it was form under a security purposes there was little progress towards the economical interactions. This is due to the external trading ties each member countries had already been involved in. Due to the colonial legacy in this region, countries tend to look upon trading partners outside the region. Intra-trading level was very low considering making up only twenty percent of the regional income. Theses different mind sets for both organizations will reflects towards the different organization structures, as we will discuss this on the next chapter of the paper.   We are going to take the different perspective view of the EC on its institutions that aided integration process and the theories behind EU integration.   ASEAN integration structure is not as varies as the EU but it is worth comparing it to the EU anyways. Integration Structures Supranational VS Authoritarianism Integration is a linkage between two or more independent actors to extend or broaden the authority through economic co-operations, losing sovereignty by changing domestic regulation and policy moving to the supranational body. The question here is why do some integration so successful and why do some don’t? The EU is one of the few organizations that had been successful with its integration. A big part of its success comes from its capability to establish institutions and policies that became clearly defined sets of rules. These sets of rules therefore became superior to domestic law of the member states of the Union. This structure that had been created by the European polity has given planting ground for intraregional trade and investment. And it had replaced and brought a war-torn Europe that was known for inner continental warfare and economic differentiations, prosperity and stability. But when comparing the EU’s success to ASEAN, it is too soon to determine if the ASEAN organization is a success or a failure. Although the ASEAN is trying to copy EU success by using and adapting to the methods used in Europe, the two regions are very different in terms of backgrounds creating their identities and the nature to co-operation between each other.    The difference level of success of any regionalism lays on it how much the regional actor can enforce their rules over national domestic law. This brings us to the institutionalization of integration. By joining the organization, state actors are expected to give up its sovereignty to the communal authority. With the case of the EU the institution that monitors the integration process is the European Court of Justice or the ECJ. The ECJ provides the jurisdiction over varies of actions, such as the actions brought to them by member states, or an individual within the community. It established the framework for the constitutionalization of the Treaty by providing links between the Court and sub national actors to their lawyers, and sub national courts. An example for this was the case of Gend and Loos in 1963 when their attempt to import goods did not fall in the legal framework of the Dutch government, but was accepted according to the Treaty of Rome, which was the product of the EU institutionalization. They have brought their case to the ECJ to determine whether they needed to follow the Dutch domestic law or the EU’s. As it turned out the Dutch government lost to the Rome regulations. This had marked the start of the EU as the correct regulation to be applied. It also marked the power of the regional body like the ECJ over the domestic national government such as the Dutch. This is one of many examples of how national government body had given up its power to the supranational authority. Therefore government has to react to the demand for integration. The court plays vital roles in monitoring and enforcing role in integration. The effectiveness of the EU lies on its ability in its enforcing mechanism. The Supremacy doctrines states that the EU has primacy over national legislation, while the Direct Effect doctrine provides the rights for the citizens of the member country the direct access to the EU court without having to go through the national government. Individuals can choose to take direct legal actions against their own government if the government fails to meet up with the rules that were agreed with the EU.   The direct intervention of the third party of a supranational institution such as the ECJ is one of the greatest successes of integration in Europe. There are numbers of different theories supporting the EU integrations in creating the supranational institution; the most common ones that are worth mentioning are theories of Functionalism, Neo-Functionalism, and Intergovernmentalism.   These are the theories circling the study of International relations that most political scientists have agreed upon.   Ã‚     Functionalism is an international relations theory that became widely known from president Woodrow Wilsons fourteen points speech. It expressed strong concern over the role of the State as a form of social organization that was becoming out of date and ineffective. It offers a counter view from that of Realism that view nation states should be driven by their own individual self-interest, functionalists’ focus on common shared interests by states and non-state actors. It view that functionalism is an effect of the process globalization which integration is triggered by the fading of state sovereignty and the advances in knowledge shared by scientists and experts effecting the tradition of policy-making.   Functionalism proposed to build a form of authority based in functions and needs, which linked authority with needs, scientific knowledge, expertise and technology, creating a supranational concept of authority.   The Coal and Steel Treaty is the evidence of the raise of a supranational body that was a product of Functionalism, which gave the body, controls and regulations to all of the coal and steel production of Western Europe.   Ã‚  Ã‚  Neo-functionalists focused their attention in the process of integration among states, i.e. regional integration. Initially, states integrate in limited functional or economic areas.   Thereafter, partially integrated states experience increasing momentum for further rounds of integration in related areas. This invisible hand of integration phenomenon was termed spill-over. by the neo-functionalist school. Although integration can be resisted, it becomes harder to stop integrations reach as it progresses.   There are two kinds of â€Å"spill-over†, which are functional spillovers and political spillovers.   Functional spill over explains the interconnections between various economic sectors and issues areas.   Political spillover explains the setting up of international institutions like the European Union and the United Nations.   Ã‚  Ã‚   Intergovernmentalism is the theory arguing Neo-Functionalism, and rejects it.   According to Standley Hoffman, any increase in power at supranational level, he argues, results from a direct decision by governments. He believed that integration, driven by national governments, was often based on the domestic political and economic issues of the day. The theory rejects the concept of the â€Å"spill-over† effect that neo-functionalism proposes. He also rejects the idea that supranational organizations are on an equal level in their political influence as national governments.   His argument lays on the fact that if Neo-Functionalism is the main theory that drives integration, then how do you explain the period of inertia in regional co-operation when there was a diverge national interests.   And the role of governments is in the unparallel national policies.   Ã‚  Ã‚   Realism is the international study theory that explains the anarchy nature of international affair could be use to conceptualize Southeast Asian states.   McCormicks comparison between Functionalisms to Realism below could be use to characterized EU to ASEAN.   As the ASEAN nations tend to focus on military security in the early stage, the evidence in this is the non-interference agreement that was signed by each member states.   While the Coal and Steel Treaty aims to maintain peace and to promote prosperity from pooling of resources through co-operation between member states.   In turn, EU nations were trying to promote security by collaborating with each other while ASEAN was trying to maintain security through building domestic power by non-interference.   The nations of SEA make their policies with the use of military force and economy, while the EU uses negotiation.   ASEAN is also known for the lack of continuity of policies from the constant shift of control over the authority and power. The EU nations, on the other hand, focus on low politics like economical and social issues.   International organizations has very limited power because the states simply do not listen to them, in the contrary, in Europe the role of government is limiting as the international organization has power to regulates policies which governments has to obey.   These points clearly show the drastic contrast between the two organizations. Comparing Functionalism to Realism John McCormick compares Functionalisms fundamental principles with Realisms thus (comments added to emphasize key distinctions): Realism Functionalism Comments Dominant goals of actors Military security Peace and prosperity security through: Power vs collaboration Instruments of state policy Military force and economic instruments Economic instruments and political acts of will State policy of assertion vs negotiation Forces behind agenda formation Potential shifts in the balance of power and security threats Initial emphasis on low politics, such as economic and social issues Agenda sought: maintenance of position vs reaching consensus Role of international organizations Minor; limited by state power and the importance of military force

Mangroves in Australia Essay -- Plants Botany Essays

Mangroves in Australia The mangrove communities of Australia are some of the most highly adaptive plant communities in the world. These plants live in an environment that is often engulfed with seawater. This environment is considered an arid environment due to the lack of fresh water. The plants of the mangrove community must develop several adaptations to deal with the environment. The environment these plants often inhabit is referred to as an intertidal zone. The intertidal zone is the transition between the salty ocean to the fresh water of the interior of the continent or island. To deal with the salty environment, mangrove plants have developed modified roots. In some species, the roots filter the incoming seawater. These modified roots also help to support the tree in the muddy substrate. The roots are considered a xeromorphic feature, a display feature that tends to conserve or retain water. These roots also provide oxygen intake by structures call pneumatophores. This ability is importa nt in times of low soil aeration. The leaves are covered with a waxy cuticle that helps retain water. In some species, the leaves are responsible for salt secretion, while others store excess salt in leaves until they fall off the tree. The mangrove species also have modified reproductive structures. Most seeds develop while still attached to the parent tree. This enhances their chance of survival. These seeds are also buoyant, which allows them to float to a less shady spot, away from the parent tree and start growing. Some species seeds shed their seed coat at particular water temperature and water salinity. Mangrove species produce different types of pollen for different plants. These different types of pollen ... ...e land (Maguire 2000). Mangroves are endangered by human development. Conservation and management techniques need to become an important issue to preserve these unique and highly advance communities. Summar The mangroves are some of the most highly evolved plant communities in the world. These plants have overcome the harsh conditions from which they live in. One of the most obvious adaptations is the modified root structures that not only help support the plant in the muddy substrate, but may aid in oxygen intake in some species. Another notable adaptation that mangrove plants exhibit is their modified reproductive structures called propagules. These seeds actually begin development while still attached to the parent tree. Mangroves also provide important services such as filtering out toxins in outgoing streams that would normally damage coral reefs.

Euripides Support of Women’s Rights Essay -- Biography Biographies Ess

Euripides Support of Women’s Rights      Ã‚  Ã‚   One can hardly deny that in Euripides’ plays women are often portrayed as weak, uncertain, and torn between what they must do and what they can bring themselves to do.   Other women appear to be the root of grave evils, or simply perpetrators of heinous crimes.   In a day when analysis of characters and plot had yet to be invented, it is easy to see why he might have been thought to be very much against women.   However, when looking back with current understanding of what Euripides was doing at the time, armed with knowledge of plot devices and Socratic philosophy, this argument simply does not hold up.   In fact, a very strong argument can be made to the opposite, that Euripides was in fact very much in support of women’s rights, and thought they were treated unfairly.      Ã‚  Ã‚  Ã‚  Ã‚   To begin to understand what Euripides was doing, it is best to understand the medium of his art: the Greek theater.   Theater was a competitive art among playwrights, with several competitions throughout the year, the greatest of which was at the Dionysian festivals in the spring.   Greek drama, tragedy in particular, had little in common with modern acting productions.   There was little or no suspense as to the outcome of the play; most all were based on Homeric tales from The Iliad and The Odyssey.   The skill, therefore, was not in creating a fascinating plot, but in the subtle changes the playwright could incorporate to increase the dramatic effect.   Changing the reasons for conflicts, dialogue, order of events, and sometimes even the outcome of the play were all ways to do this.   With all these devices available to the fifth century playwright, what made Euripides so special that he was almost exclusiv... ... Euripides. Medea. Trans. Paul Roche. New York: Norton, 1974. Euripides. The Bacchae. Trans. Paul Roche. New York: Norton, 1974. Euripides. Andromache. Trans. John McLean. New York: Dial Press, 1936. Euripides. Hippolytos. Trans. John McLean. New York: Dial Press, 1936. Euripides. Trojan Women. Trans. John McLean. New York: Dial Press, 1936. Euripides. Electra. Trans. John McLean. New York: Dial Press, 1936. Nietzsche, Friedrich. The Birth of Tragedy. Trans. Clifton Fadiman. New York: Dover Publications, 1995. Perseus Encyclopedia. Revised 1999. Tufts University. www.perseus.tufts.edu/cgi-bin/encyclopedia?entry=Euripides>. Powell, Anton, ed.   Euripides, Women, and Sexuality.   New York: Routledge, 1990. March, Jennifer.   â€Å"Euripides the Mysogynist?†Ã‚   Euripides, Women, and Sexuality.   Ed. Anton Powell.   New York: Routledge, 1990.

John Dryden: England’s Controversial and Exceptional Genius

John Dryden was England’s most outstanding and controversial writer for the later part of the seventeenth century, dominating the literary world as a skilled and versatile dramatist, a pioneer of literary criticism, and a respected writer of the Restoration period. With Dryden’s great literary and critical influence on the English society during the Restoration period he has made a name for himself, which will be studied and honored for years to come. John Dryden was born in Northamptonshire, in 1631. His parents were Erasmus Dryden and Mary Pickery. They were both from wealthy and respected families in Northamptonshire. The Drydens were known for wisdom and great tradition all over England and were well-equipped with large estates and vast lands (Ward 5). Dryden’s father, Erasmus, was a justice of the peace during the usurpation, and was the father of fourteen children; four sons, and ten daughters. The sons were John, Erasmus, Henry, and James; the daughters were Agness, Rose, Lucy, Mary, Martha, Elizabeth, Hester, Hannah, Abigail, and France (Kinsley 34). Dryden was also a religious man. He had as much faith in the Lord as he did in his pen. He belonged to the Church of England all his life until converting to Catholicism due to the change of the throne. He was baptized at All Saints Church in Aldwinule, Northamptonshire ten days after his birth (Hopkins 75). Dryden, growing into a young man, began his education in his hometown. There he took the basic classes. He furthered his education at Westminister School in London. Here, he attended school for about twelve hours a day, beginning and ending at six. At Westminister he studied history, geography, and study of the Scripture, plus all the basics. After Westminister he Cunningham 2 attended Cambridge University (Hopkins 14). While attending Cambridge University, he excelled to the top of his class and was a standout student. John Dryden was the greatest and most represented English man of letters of the last quarter of the seventeenth century. From the death of Milton in 1674 to his own in 1700, no other writer can compare with him in versatility and power (Sherwood 39). He was in fact a versatile writer, with his literary works consisted of tragedy, comedy, heroic play, opera, poetry, and satire. Although he did write most of his important original poems to serve some passing political purpose, he made them immortal by his literary genius (Miner 3). John Dryden was the type of man who was always busy with some great project. He would never put full time and concentration into his work. He would quickly finish a project, careless of perfection, and hurry off to begin another, which was not a tempting deal on either the author’s side nor the reader’s side because Dryden lived in a time where there were few well-printed works (Hopkins 1). So much of his work consisted of numerous errors, misprints, and lost pages. Several critics have attempted to revise and correct his work but usually for the worse ( Harth 3). Despite his popularity during the Restoration and even today, little is known about John Dryden except what is in his works. Because he wrote from the beginning through the end of the Restoration period, many literary scholars consider the end of the Restoration period to have occurred with Dryden’s death in 1700 (Miner 2). Surviving Dryden was his wife Lady Elizabeth and there were three sons, to whom he had always been a loving and careful father. John, his oldest son, followed his father in death only three years later in April of 1700. His wife, the â€Å"Widow of a poet,† died shortly after his death in the summer of 1714 at the age of 78 (Bredvold 314). Dryden certainly attained his goal of popularity especially after his death. He became this Cunningham 3 through his â€Å"achievements in verse translations, the first English author to depend for a livelihood directly on the reading public and opening the future of profitable careers for great novelists during the next two centuries† (Frost 17). The Restoration period was a time of great literature and outstanding writers, but, with all the talent in this century, there were also many problems. The Restoration was an angry time in literary history. Writers threw harsh blows at one another, not with fists but with paper and ink. It was an age of plots, oaths, vows and tests: they were woven into the â€Å"fabric of everyday life, and hardly a person in England escaped being touched by them† (Hammond 131). During this time he wrote about what was going on in life activities quite often in his work. At this time there was a major controversy over the conversion from Protestantism to Roman Catholicism. Dryden’s church was in a strange and uncomfortable position. Since the time of the Restoration it had been an underground organization because it was regarded as the enemy of the English monarchy. Some of the members have been accused, and others falsely accused, of setting plots against the crown (Hopkins 85). In 1663, Dryden, â€Å"under the cloud of some personal disgrace,† married Sir Robert Howard’s sister, Lady Elizabeth. The marriage provided no financial advantages or much compatibility for the couple, but Dryden did gain some social status because of her nobility. Because of his social success, Dryden was made a member of the Royal Society that same year. Since he was a non-participating member and did not pay his dues, his membership was later revoked. In 1664, he wrote a poem honoring his brother-in-law, Sir Robert Howard, with whom Dryden remained involved personally and professionally for some time. In 1668, he was Cunningham 4 named Poet Laureate and was offered a share in the Theater Royal’s profits in exchange for his plays. This is where he earned a large portion of his income, and ensured his financial stability for the next several years. However, in 1689 when William and Mary took the throne they replaced John Dryden, a Catholic; and made Thomas Shadwell, a Protestant, the new Poet Laureate (Verrall 6). John Dryden was a poet for about forty years. He was formally known as a â€Å"public poet† because a great amount of his poetry dealt with public issues (Harth 3). The explanation for Dryden’s late development as a poet was due to the simple fact that he had nothing to say. In Dryden’s poems, the descriptions he gave avoided unique, concrete details; he preferred general terms. When he described men and women, he gave his attention to moral qualities, not physical appearance. He usually glorified the lower social class and put the upper social class in a shadow (Sherwood 7). Many of Dryden’s poems were congested with printing errors and misspelled words, although, the reasons for this were not totally his fault. There was not a great printing process during this time and many careless mistakes in printing were caused by neglectful workers (Sargeant 10). John Dryden is a poet who left a firm impression of his character in this world; he is known as a public figure, respected literary critic, popular dramatist, and strong supporter of religion and politics (Salvaggio 13). Dryden’s poetry has been divided into two time periods of his career. The first was during the Restoration period and ended in 1667. He did not write another poem for fourteen years; during this time he was writing plays and critiques. The second period began during the later part of his life and ended in 1681 (Harth 3). Some of Dryden’s more popular poems â€Å"The Cock and the Fox,† â€Å"All For Love,† â€Å"Antony and Cleopatra,† â€Å"Absalom and Achitophal,† and his most famous â€Å"Mac Cunningham 5 Flecknoe. † In the poem â€Å"All For Love,† it portrays the love story between Cleopatra, the breath-taking, beautiful, Queen of the Nile and her lover Antony. He also knew that when writing this poem it would be nothing new to the poetic world (Dryden 14). â€Å"All For Love† is a pale, beautiful play. The theme â€Å"All For Love† was meant to be that â€Å"punishment inexorably follows vice and illicit love. Actually, the motivation of the play is a conflict between reason and passion, and it is this conflict that makes â€Å"All For Love† truly representative of the Restoration Period and the battle of ideas that settled beneath† (Dryden 25). The greatest of his poems was â€Å"Absalom and Achitophel. † He wrote this while he was Poet Laureate, the national poet of a country (Hopkins 5). In this poem he described a political predicament that is described by characters from the Bible. He uses a vast amount of symbolism in the story. â€Å"Absalom and Architophel† represents his lifelong affinity for seeing the present in terms of the past (Miner 15). One of his most famous poems is â€Å"Mac Flecknoe. † He destroys Thomas Shadwell by taking very crude and harsh blows on the man. However, Dryden refers to Shadwell’s appearance to only imply that he is fat: â€Å"A Ton of Man in thy Large bulk is writ, but sure tho’rt but a kildrekin of wit† (Sherwood 7). There is nobody of English criticism that is more alive, that brings readers more directly into contact with literature, than John Dryden. One can never predict what will arise with Dryden’s criticism, but it will be far more promising than any other (Mc Henry 25). John Dryden is known as â€Å"the father of English Criticism† (Osborn 136). But, other studies and opinions show that his critical writings are known to quite often derivative, self-contradictory, rambling, inexact, at times over-specialized, and at others too sweeping (Hopkins 137). Cunningham 6 Dryden’s earliest critical essay was written in 1664, about his first verse play, The Rival Ladies. From this date until his death in 1700, Dryden scarcely passed a year without writing a preface, an essay, a discourse, a literary biography or some piece of criticism (Osborn 179). His criticism has not been viewed in the correct ways in some cases. It has often been praised for its minor virtues, and too little admired for its major ones. â€Å"His criticism is great in contrast as well as in style† (Hammond 179). John Dryden’s critical qualities are handsome ones, preferable to most. He has confidence in his basic assumptions and more gracefully within his tradition. Another great strength of his, is that he plays example against theory and theory against example; Dryden also possesses many more admiring qualities (Hammond 5). As a well-respected critic as he is Dryden has a habit of telling what he is thinking at the time of composition. His prefaces and prologues have the quality of studio talk in which the artist speaks of what he has tried to do and how he has done better, or worse, than others. He gives his views at the time, he may have different views at other times that are more educated, but he gives the views which engage him at the moment (McHenry 39). Criticism of Dryden in the half-century following his death is sparse, and contributions from the major men of letters are disappointingly casual and undeveloped. However, most likely the best criticism of Dryden during the period after his demise comes from â€Å"Dennis, Congerer, and Garth. † There is passion as well as admiration in Dennis’s remarks for Dryden’s poetry (Bredvold 14). He is a critic more than a theorist, meaning he judges poetry thoughtfully by talking incomparably well about the poetry. However, he also likes to think and to speak of his thinking to explore and mediate literary principles. John Dryden wrote with ease and at times carelessly, but he knew where he stood (Hammond 1). Cunningham 7 His poetry was often seen as a pure, rich, metrical energy, and formally proper to the genre. â€Å"It is throughout its whole range, alive with a special kind of feeling† (Osborn 181). John Dryden was engaged in literary controversy his entire literary career and life. He feuded with famous writers such as Sir Robert Howard, Thomas Shadwell, Andrew Marvell, Thomas Rymar, and many others. Shadwell was the most unfortunate foe of them all. If he had never quarreled with Dryden he would not have been known today as one of the four great comic playwrights of the Restoration period (Dryden 1). Shadwell’s and Dryden’s literary quarrel developed by the means of critical comments in prologues, epilogues, prefaces, and dedications written between 1668 and 1678. Dryden’s â€Å"Mac Flecknoe† was a major issue in the dispute between Dryden and Shadwell (Dryden 4). In â€Å"Mac Flecknoe,† Shadwell’s memory is kept alive, but has also been branded forever as horrible writer and a disgrace to the history of English writers. â€Å"Mac Flecknoe† is Dryden’s most delightful poem. It reveals Dryden’s great writing talents as poet and satirist. As he accuses Shadwell of â€Å"borrowing† from other authors. He also indicted Shadwell of â€Å"consistently stealing,† but the charges were also greatly exaggerated. However, Dryden admitted that he was guilty of â€Å"borrowing† from other authors, but he also mentioned that Charles II said that he wished those incriminated for stealing would steal plays like Dryden’s (Dryden 18). At some point Shadwell had got on good terms with Dryden, good enough at least for Dryden to provide the prologue to one of Shadwell’s plays. It might have been the prologue the others, but still it served as a prologue to one of Shadwell’s. They had to have developed some sort of friendship or came to know each other. Then something happened and the time for reconciliation had passed. In the same year in which he wrote that prologue for Shadwell he also wrote â€Å"Mac Flecknoe† to put an Cunningham 8 end to the feuding, and Shadwell became the â€Å"unforgiven butt of his ridicule† (McHenry 47). Dryden was an exceptional author that just did not make as big as others. His literary reputation suffers greatly from the simple fact that not many know of him. He is the man who wrote â€Å"Absalom and Architophel,† â€Å"Mac Flecknoe,† and who precedes Pope. He wrote not only great satirical, but great love poems, great political poems, and great religious poems. Beyond those poems he wrote many great passages of poetry. He wrote an astounding amount of good poetry, probably more than any other poet in the language except Shakespeare and Milton (Hammond 67). The English author John Dryden called himself Neander, the â€Å"new man,† in his Essay of Dramatic Poesy, and implied that he was a spokesman for the concerns of his generation and the embodiment of it’s tastes. He achieved a prominence that supported his claim. Dryden excelled in comedy, heroic tragedy, verse satire, translation, and literary criticism; genres that his contemporaries and later readers have defined as representative of the Restoration period. John Dryden’s lasting legacy will be defined by his unequaled, excellent criticisms of literature and his outstanding poetry. He developed the model for modern English prose style and set the tone for 18th century English poetry. His memorable works helped influence much of the writings that come from England to this day. Translations are another major reason why people will remember Dryden. He took authors from previous eras works and interpreted them into something superior and moved them to a greatness previously believed unattainable. His considerable accomplishments assured Dryden’s place in literary history and, through their influence on such writers as Alexander Pope, determined the course of literary history for the next generation.

Tay Sachs Is Fatal Health And Social Care Essay

By 2 years, Dj responded to auditor cues more than ocular 1s. He no longer could keep up his caput or perform simple activities such as turning the pages of a book.Nystagmus and a â€Å" cherry ruddy † was noticed by the paediatric eye doctor by so which would farther assist in his diagnosing. By this clip, he had regressed to a six months developmental degree ; his balance and vision were truly acquiring worse. At 2yrs, Dj was diagnosed with Tay Sachs by the brain doctor after his changeless visits and ratings. After this diagnosing a Deoxyribonucleic acid analysis for DJ was done to seek to happen the exact defect. A ruddy cell and leucocyte hex A degrees for his parents was done every bit good, to corroborate that both of them were bearers which was proven three hebdomads subsequently. The exact mutant in DJ could non be found which was non a surprise as more than 50 known mutants for this disease be but the research labs in the United States routinely trial for merely nine of the most common 1s. By two and a half old ages, his weight increased from 20 pounds at 2yrs to 25 lbs and he grew a few inches taller. At this pointing clip he had ictuss and experient minutes of agitating when being moved. Excess mucous secretion began constructing up in his pharynx which would subsequently after his lungs and external respiration. He was placed on Diamox for 6 months by so which aided him a spot with grow. His get downing physiological reactions weakened and congestion increased. He was besides placed on a tranquillizer which assisted in diminishing his shudders. By 3 year, he used a suction machine to take the extra mucous secretion so that he could be fed passed. His developments were being delayed further and he developed pneumonia as he became more susceptible to infections. As Dj turned four old ages, he no longer ate chiefly by oral cavity, but took repasts through a NG tubing. Although he did non take medicine to command his ictuss, he now took three medicines daily for other symptoms of the disease: A DiamoxA to cut down the force per unit area on his encephalon, A RobinulA to command extra secernments, andA ZantacA to command the sourness in his stomach.DJ was by no agencies lethargic or vegetive which is common for kids around that age enduring from the disease. He was alert for most of the twenty-four hours, and he moved himself around a batch, turned his ain caput and stretched his organic structure at will. He was really loose, and did non hold a job with contractures or palsy. By 5yrs, DJ received his repasts and medicines through his NG months.A He took three medicines daily for symptoms of the disease: A DiamoxA ( acetazolamide ) to cut down the force per unit area on his encephalon, A robinulA ( glycopyrrolate ) to command extra secernments, andA ativanA ( Ativan ) to assist him kip at dark. He retained some scope of motion eg.turning his ain caput, yawning and stretching his whole organic structure. His parents exercised his carpuss and pess more as they tended to drop down. Daily therapy was given to him by his parents which assisted in diminishing his ictus episodes and retaining some physical motion. Due to limited gesture he developed force per unit area sores as he invariably slept on one side of his organic structure. As small Dj approached his sixth birthday he started holding jobs such stiffness with contractures. It became really hard for him to make certain actions such as dividing his articulatio genuss or conveying his custodies away from his thorax as his shoulder blades would lift when his weaponries were lifted. He was still undergoing physical therapy in order to seek opening up his thorax to do it easier for him to take a breath. Gentle scope of gesture exercisings for his pess and custodies were done to loosen up the articulation in these countries. He experienced acidic belch as good which was discomforting for him. A few yearss before his birthday, Dj became one more statistic for Tay sachs. 1Today, most patients are seen in households with no anterior history of the disease because the recessionary cistron can be carried without being expressed through many coevalss. Carrier testing and familial guidance have made this disease rare in those at known hazard. While there are certain populations at higher hazard, A anyoneA can be a Tay-Sachs bearer.Pathogenesis and SymptomsTay sachs is a fatal autosomal recessionary familial upset in kids that causes the progressive devastation of the cardinal nervous system due to mutants in the HEXA cistron which encodes the alpha sub unit of the lysosomalA enzymeA beta-N-acetylhexosaminidase A. ( 3 ) In order to get the disease, both parents must be bearers of this mutauted HEX A which is to be inherited by an progeny. Possessing the 2 mutated HEX A is identified to be a 1 in 4 opportunity or 25 % .TheA HEXAA cistron provides instructions for doing portion of the enzyme beta-hexosaminidase A, which plays a of import portion in the encep halon and spinal cord. This enzyme is located in lysosomes which is why the disease is classified as a lysosomal storage disease or GM2 gangliosidosis. ( 2 ) Within the lysosomes, beta-hexosaminidase A helps interrupt down a fatty substance GM2 ganglioside. Mutants in theA HEXAA cistron disrupt the activity of beta-hexosaminidase A, which prevents the enzyme from interrupting down GM2 ganglioside. As a consequence, this substance accumulates to toxic degrees, peculiarly in nerve cells in the encephalon and spinal cord. Progressive harm caused by the buildup of GM2 ganglioside leads to the devastation of these nerve cells, which causes the marks and symptoms of Tay-Sachs disease.[ 2 ] Tay Sachs have been linked to about 90 mutants in the HEX A cistron with increasing Numberss. The type of mutants range from point mutants, omissions, splicing site mutants and many others. ( 1 ) Any of these mutants will merely increase the GM2 in the cells suppressing the map of the enzyme hexosaminidase.[ 3 ]A A four base brace interpolation inA exonA 11 ( 1278insTATC ) consequences in an alteredA reading frameA for the HEXA cistron. This mutant is the most prevailing mutant in the Ashkenazi Jewish population, and leads to the childish signifier of Tay-Sachs disease.[ 4 ]A mutant that is unrelated to the prevailing Ashkenazi mutant, a long sequence omission, occurs with similar frequence in households with Gallic Canadian lineage, and has the same pathological effects.This depicts that the fluctuations in the different mutants may hold similar symptoms. The different mutants may besides impact the type of Tay sachs which occurs. Three different types of Tay sachs has been identified ; childish, juvenile and grownup oncoming. Each is characterized by assorted mutants at different phases of the life rhythm. The assorted types and symptoms associated with them as are follows: Childish TSD: InfantsA withA Tay-Sachs diseaseA appear to develop usually for the first six months of life. Then, asA nerveA cells become distended with gangliosides, a grim impairment of mental and physical abilities occurs. The kid becomes blind, deaf, and unable to swallow.A MusclesA get down to atrophy andA paralysisA sets in. Death normally occurs before the age of five.[ 5 ] Late oncoming or Adult Onset ( LOTS ) ; seen in people between their 20s and 30s. This type is normally non-fatal and is seen due to diverse mutant forms. At first, the patient is heterozygous for the mutated cistron later developing two mutated HEXA cistrons that can demobilize, inhibit or change the actions of the hexosamamidase enzyme. This therefore illustrates that one time the patient has one transcript of the HEXAA geneA that still enables some hexosaminidase A activity, a ulterior onset signifier of the disease occurs. The symptoms typically are dysarthria, A proximalA ( bole ) A musculus failing, A tremorandA ataxy. Muscle spasms, particularly in the legs at dark, andA fasciculationsA ( musculus vellication ) are common. Not all symptoms are present in every person affected by the disease ; failing of the proximal musculuss, nevertheless, is a symptom common to all. Examples of trunk musculus failing may include trouble lifting from a sitting place, problem acquiring out of bed, fighting to equilibrate while acquiring dressed. Symptoms ofmanic-depressionA orA psychoticA episodes may be present in approximately 30 % of affected individuals.[ 6 ] Juvenile TSD ; mutants are similar to that found in the grownup onset type of TSD except that the disease occurs between the ages of 2 to 10 normally. This signifier of TSD is highly rare. They develop cognitive, motor, address, andA get downing troubles, ataxy and spasticity. These patients normally die between 5-15 old ages.DiagnosisDuring gestation, many antenatal trials can be used to name Tay-Sachs in the foetus before birth such as Amniocentesis and Chorionic Villus Sampling ( CVS ) .[ 7 ]Between the 10th and 12th hebdomads of gestation, an anticipant female parent can acquire a chorionic villus sampling, or CVS, in which a little sample of the placenta is drawn into a needle or a little tubing for analysis. A reddish topographic point in the dorsum of the oculus is displayed and is clearly seeable when viewed by an eye doctor or an oculist. In childish TSD patients, parents normally notice developmental holds but baby doctors frequently dismiss these concerns as normal slow developments. Around 10-14 months of age, TSD patients exhibit problem trailing or concentrating their eyes, which leads to an ophthalmologist visit. The reddish topographic point is rapidly seen and an initial diagnosing of Tay-Sachs or similar annihilating disease is made. Genetecist and brain doctor can normally name this disease every bit good due to the complications noted. Children with Juvenile Tay-Sachs or late oncoming TSD OR grownup TSD with chronic complications normally take a longer clip period to be diagnosed. . Many affected kids and grownups express assorted emotions when eventually acquiring a diagnosing. The enzyme check is a biochemical trial that measures the degree of enzyme in a individual ‘s blood. Babies, kids and grownups have low or non-existent degrees of Hex-A in their organic structure fluid and cells are diagnosed with Tay-Sachs. Low or non-existent degrees of Hex A enzyme will be noted in this disease.[ 8 ] An enzymatic trial can besides be done in order to look into the degree of enzymes in the blood. The public presentation of the HexA cistron can be checked in the serum and leucocytes.TreatmentTays Sachs has no remedy. The patients are merely treated in a mode which can help them in being comfy for the remainder of their lives. In add-on to this, household support can be given to assist the household members cope with the effects of this disease. Each of these intervention methods can be seen in our sample instance of small Dylan. Such methods are as follows ; 1 ) Medicines: used to forestall ictuss. Such medicines are tranquillizers, diamox ( for encephalon force per unit area alleviation ) , robinul ( extra secernment control e.g the extra mucous secretion ) 2 ) Respiratory attention: Tay-Sachs disease normally leads to an accretion of mucous secretion in the lungs. To cut down the sum of mucous secretion nowadays, thorax physical therapy ( CPT ) can be done. Parents of kids enduring from the disease are trained to transport out CPT. 9Children with Tay-Sachs disease are at high hazard of respiratory infections, which affect the lungs and cause external respiration jobs, and need to be carefully monitored and provided with prompt intervention. 3 ) Use of assistive devices: As seen in the instance of Dj, get downing physiological reactions weaken as the disease progresses doing it rather hard when feeding. Devicess can be used in order to feed the patients as the nutrient or fluid may come in the lungs doing sever respiratory jobs once more. The devices used are:[ 10 ]Nasogastric ( NG ) tubingthis is a tubing inserted through the olfactory organ to the tummy.Transdermal Esophago-Gastrostomy ( PEG ) tubingPEG tubings are placed through the venters into the tummy during a surgical process that is normally done by a physician specializing in gastroenterology or radiology. This option is more lasting than the NG tubing. 4 ) Physical Therapy:[ 11 ]Physical therapy for musculus and joint stimulation which increases flexibleness and scope of gesture. This is done by rub downing the affected organic structure parts. This helps detain joint stiffness or contractures cut downing or detaining the loss of map or the hurting that can ensue from contractures. hypertext transfer protocol: //www.djhomepage.com/ hypertext transfer protocol: //ghr.nlm.nih.gov/condition/tay-sachs-disease hypertext transfer protocol: //www.goldbamboo.com/topic-t2982-a1-6Tay-Sachs_Disease.html hypertext transfer protocol: //www.ntsad.org/ hypertext transfer protocol: //www.mayoclinic.org/tay-sachs-disease/treatment.html hypertext transfer protocol: //en.wikipedia.org/wiki/Tay % E2 % 80 % 93Sachs_disease hypertext transfer protocol: //kidshealth.org/parent/medical/genetic/tay_sachs.html # hypertext transfer protocol: //www.ntsad.org/S02/S02TS_diag.htm